Zinedine Zidane faces his toughest test since becoming Real Madrid coach as Athletic Bilbao visit the Santiago Bernabeu on Saturday.
Real’s title hopes hang by a thread as they are four points adrift of leaders Barcelona, who also have a game in hand.
Zidane will also get his first taste of Champions League action as a coach later in the week as Madrid travel to Roma, but Cristiano Ronaldo insists they are not ready to give up on the league to focus on Europe yet.
“The players are going to give everything on the field to try and win the title and the Champions League,” he told the club’s website.
Madrid have injury worries as their only specialised left-back Marcelo is sidelined by a dislocated shoulder, while Gareth Bale remains out with a calf injury.
Athletic also have key players missing as Inaki Williams and Mikel San Jose are both suspended.